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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHAT
All Species:
5.76
Human Site:
S497
Identified Species:
10.56
UniProt:
P28329
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28329
NP_066266.3
748
82536
S497
E
I
Q
G
H
L
A
S
S
A
E
K
L
Q
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109211
626
70697
D392
I
T
P
E
I
K
S
D
I
E
K
A
K
Q
N
Dog
Lupus familis
XP_543902
686
76910
Y452
K
N
L
D
F
T
V
Y
K
F
D
I
F
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q03059
641
71834
Y407
K
N
L
D
F
I
V
Y
K
F
D
N
Y
G
K
Rat
Rattus norvegicus
P32738
640
71845
Y406
K
N
L
D
F
I
V
Y
K
F
D
N
Y
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509108
643
72737
Y409
K
N
L
D
F
V
V
Y
K
F
E
N
Y
G
K
Chicken
Gallus gallus
Q90YJ9
640
72605
Y406
K
N
L
D
F
I
A
Y
K
F
V
N
Y
G
K
Frog
Xenopus laevis
Q7ZXE1
659
74538
L425
H
F
N
L
D
D
S
L
K
A
A
I
T
D
A
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
F403
L
D
M
N
V
H
K
F
T
G
Y
G
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
A474
L
Q
L
R
F
A
Q
A
S
K
S
V
D
K
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
L393
S
E
N
S
R
N
I
L
K
K
Q
A
E
V
F
Sea Urchin
Strong. purpuratus
XP_001185550
675
75787
V441
K
A
Q
I
T
Y
A
V
S
D
A
D
V
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
E436
P
K
I
H
K
A
I
E
S
A
Q
L
Q
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
37.8
77.9
N.A.
74.7
74.7
N.A.
68.4
66
24
57
N.A.
37.5
N.A.
29.2
46.3
Protein Similarity:
100
N.A.
55.7
82.4
N.A.
79.1
79
N.A.
76.5
74
40.6
68.8
N.A.
56.1
N.A.
45.1
62.4
P-Site Identity:
100
N.A.
6.6
0
N.A.
0
0
N.A.
6.6
6.6
6.6
0
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
N.A.
20
20
N.A.
26.6
26.6
N.A.
26.6
26.6
13.3
13.3
N.A.
20
N.A.
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
16
24
8
0
24
16
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
39
8
8
0
8
0
8
24
8
8
8
0
% D
% Glu:
8
8
0
8
0
0
0
8
0
8
16
0
8
8
0
% E
% Phe:
0
8
0
0
47
0
0
8
0
39
0
0
8
8
16
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
8
0
39
0
% G
% His:
8
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
8
8
24
16
0
8
0
0
16
0
0
0
% I
% Lys:
47
8
0
0
8
8
8
0
54
16
8
8
16
16
47
% K
% Leu:
16
0
47
8
0
8
0
16
0
0
0
8
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
16
8
0
8
0
0
0
0
0
31
0
0
8
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
16
0
0
0
8
0
0
0
16
0
8
16
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
0
8
0
0
16
8
31
0
8
0
0
0
0
% S
% Thr:
0
8
0
0
8
8
0
0
8
0
0
0
8
0
0
% T
% Val:
0
0
0
0
8
8
31
8
0
0
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
39
0
0
8
0
31
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _